Intensive Care Unit-Acquired Weakness in Pediatrics: A Literature Review: Pediatric ICU- Acquired weakness

Amal Abu Libdeh; Hashem Alhanaktah; Eyad Al Masoud; Anas Zayad; Ahmad Al-Loubani

doi:10.58877/japaj.v2i1.185

Authors

Amal Abu Libdeh Department of Pediatrics, The University of Jordan, Amman, Jordan. https://orcid.org/0000-0001-5409-0230
Hashem Alhanaktah Faculty of Medicine, Hashemite University, Amman, Jordan
Eyad Al Masoud Faculty of Medicine, Jordan University of Science and Technology, Amman, Jordan
Anas Zayad Faculty of Medicine, The University of Jordan, Amman, Jordan
Ahmad Al-Loubani Department of Anesthesia, Al-Bashir Hospital, Amman, Jordan

DOI:

https://doi.org/10.58877/japaj.v2i1.185

Keywords:

Critical illness, children, weakness, myopathy, polyneuropathy, pediatric, Pediatric Critical Care, Intensive Care Unit

Abstract

Pediatric patients admitted to the intensive care unit may develop a form of muscle weakness termed Intensive Care Unit Acquired Weakness (ICU-AW), which remains relatively challenging to diagnose and manage. This condition may not be as frequent in pediatrics compared to adults, yet it represents a debilitating complication among pediatric ICU patients with notable short and long-term consequences. Diagnosis relies on history and physical exam, aided by electrophysiological studies and muscle biopsies. Serial muscle ultrasound is emerging as a reliable method for early detection of muscle wasting. Preventive measures include modifying risk factors and delaying parenteral nutrition. While no definitive treatment has been identified, early mobilization, and limiting the use of sedatives may influence the outcome of this condition in pediatrics. More data is needed to assess the incidence and prognosis of pediatric ICU-AW.

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