The Jordanian Kidney Transplant Experience: A Glorious Past and a Challenging Present

Mohammad Al-thnaibat; Mohammad Balaw; Mohammed Al-Aquily; Reem Ghannam; Omar Mohd; Firas Alabidi; Rania Jaber; Suzan Alabidi; Badi Rawashdeh

doi:10.58877/japaj.v1i3.82

Authors

Mohammad Al-thnaibat Assistant professor, Department of Internal Medicine, Faculty of medicine, Hashemite University, 13133, Zarqa, Jordan.
Mohammad Balaw Hashemite University
Mohammed Al-Aquily College of Medicine, Hashemite University, 13133, Al-Zarqa, Jordan
Reem Ghannam College of Medicine, Hashemite University, 13133, Al-Zarqa, Jordan
Omar Mohd College of Medicine, Hashemite University, 13133, Al-Zarqa, Jordan
Firas Alabidi Jordan University of Science and Technology, Irbid, Jordan https://orcid.org/0009-0001-9879-4763
Rania Jaber Department of Sociology, School of Arts, University of Jordan
Suzan Alabidi Al Ain University
Badi Rawashdeh Medical College of Wisconsin, division of transplant surgery, Milwaukee, Wisconsin, USA

DOI:

https://doi.org/10.58877/japaj.v1i3.82

Keywords:

kidney transplant, kidney paired exchange, end stage renal disease, kidney donation, Jordanian experience

Abstract

Jordan was one of the first Arab countries to enact legislation governing organ donation and transplantation. Jordan has seen an increase in the frequency of kidney transplants performed utilizing organs from living donors since that time. Jordan has been a reputable regional center for kidney transplantation and has a long history of excellence in the field.

Jordan's low rate of kidney transplants from deceased donors, Despite the legality of the Jordanian constitution, the availability of highly skilled nephrologists and transplant surgeons as well as advanced health care is quite alarming and could be caused by a number of different factors. The absence of a formal government plan to control brain death donation is the most important factor.

The goals of this study are to provide a description of the current state of kidney transplantation in Jordan, a summary of the most significant barriers to expanding kidney transplantation efforts that focus on kidneys donated by deceased donors, and suggestions for increasing the number of kidney transplants from brain dead donors.

Author Biography

Mohammad Al-thnaibat, Assistant professor, Department of Internal Medicine, Faculty of medicine, Hashemite University, 13133, Zarqa, Jordan.

Assistant professor, Department of Internal Medicine, Faculty of medicine, Hashemite University, 13133, Zarqa, Jordan.

References

Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LYC, et al. Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and Recipients of a First Cadaveric Transplant. New England Journal of Medicine. 1999 Dec 2;341(23):1725–30. DOI: https://doi.org/10.1056/NEJM199912023412303

S A Babloyan. Comparative assessment of the quality of life of kidney transplant recipients and hemodialysis patients. Urologiia.

Tonelli M, Wiebe N, Knoll G, Bello A, Browne S, Jadhav D, et al. Systematic Review: Kidney Transplantation Compared With Dialysis in Clinically Relevant Outcomes. American Journal of Transplantation. 2011 Oct;11(10):2093–109. DOI: https://doi.org/10.1111/j.1600-6143.2011.03686.x

Axelrod DA, Schnitzler MA, Xiao H, Irish W, Tuttle-Newhall E, Chang SH, et al. An economic assessment of contemporary kidney transplant practice. American Journal of Transplantation. 2018 May;18(5):1168–76. DOI: https://doi.org/10.1111/ajt.14702

Hammad S, Albreizat AH. Living-Donor Organ Donation: Impact of Expansion of Genetic Relationship. Experimental and Clinical Transplantation. 2019 Jan;17(Suppl 1):1–5. DOI: https://doi.org/10.6002/ect.MESOT2018.L24

The National Strategy for Health Sector in Jordan 2015- 2019. 2019 Apr.

INTERNATIONAL REGISTRY IN ORGAN DONATION AND TRANSPLANTATION. INTERNATIONAL REGISTRY IN ORGAN DONATION AND TRANSPLANTATION.

The Hashemite Kingdom of Jordan Ministry of Health Non-Communicable Diseases Directorate National Registry of End Stage Renal Disease (ESRD) 12 th Annual Report 2019 [Internet]. [cited 2022 Oct 29]. Available from: https://www.moh.gov.jo/ebv4.0/root_storage/en/eb_list_page/12th_annual_report_esrd_2019.pdf

Shaheen FAM, Al-Attar B, Ahmad MK, Follero PM. Burden of disease: Prevalence and incidence of endstage renal disease in Middle Eastern countries. Clin Nephrol. 2020 Jan 1;93(1):120–3. DOI: https://doi.org/10.5414/CNP92S121

Malekmakan L, Tadayon T, Roozbeh J, Sayadi M. End-stage Renal Disease in the Middle East: a Systematic Review and Meta-analysis. Iran J Kidney Dis. 2018 Jul;12(4):195–203.

National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, US Department of Health and Human Services. United States Renal Data System. 2020 USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States. 2020.

Waddah W. Saleh, Ghazi Sharkas, Dr. Nashaat Taani. The Hashemite Kingdom of Jordan Ministry of Health Non-Communicable Diseases Directorate National Registry of End Stage Renal Disease (ESRD) 13 Th Annual Report 2020. . 2023 Apr.

Kandaswamy R, Kasiske B, Ibrahim H, Matas AJ. Living or deceased donor kidney transplants for candidates with significant extrarenal morbidity. Clin Transplant. 2006 May;20(3):346–50. DOI: https://doi.org/10.1111/j.1399-0012.2006.00492.x

Naderi GH, Mehraban D, Kazemeyni SM, Darvishi M, Latif AH. Living or Deceased Donor Kidney Transplantation: A Comparison of Results and Survival Rates Among Iranian Patients. Transplant Proc. 2009 Sep;41(7):2772–4. DOI: https://doi.org/10.1016/j.transproceed.2009.07.041

Abdulrazeq F, Matsumoto M, Zourob M, Al-Dobai A, Zeyad K, Marwan N, et al. Barriers in knowledge and attitudes regarding organ donation among Urban Jordanian population. Saudi Journal of Kidney Diseases and Transplantation. 2020;31(3):624. DOI: https://doi.org/10.4103/1319-2442.289449

Katz-Greenberg G, Shah S. Sex and Gender Differences in Kidney Transplantation. Semin Nephrol. 2022 Mar;42(2):219–29. DOI: https://doi.org/10.1016/j.semnephrol.2022.04.011

Glander P, Budde K, Schmidt D, Fuller TF, Giessing M, Neumayer HH, et al. The “blood group O problem” in kidney transplantation--time to change? Nephrology Dialysis Transplantation. 2010 Jun 1;25(6):1998–2004. DOI: https://doi.org/10.1093/ndt/gfp779

Salvadori M, Tsalouchos A. Current protocols and outcomes of ABO-incompatible kidney transplantation. World J Transplant. 2020 Jul 29;10(7):191–205. DOI: https://doi.org/10.5500/wjt.v10.i7.191

Al-Qerem W, Carter N, Ling J. Attitudes to Organ Donation and Transplantation: An Insight From Jordan. Experimental and Clinical Transplantation. 2022 Jun;20(6):602–8. DOI: https://doi.org/10.6002/ect.2021.0419

Akbulut S, Ozer A, Firinci B, Saritas H, Demyati K, Yilmaz S. Attitudes, knowledge levels and behaviors of Islamic religious officials about organ donation in Turkey: National survey study. World J Clin Cases. 2020 May 6;8(9):1620–31. DOI: https://doi.org/10.12998/wjcc.v8.i9.1620

Chamsi-Pasha H, Albar MA. Do not resuscitate, brain death, and organ transplantation: Islamic perspective. Avicenna J Med. 2017;7(2):35–45.

Bani Hani A, Bsisu I, Shatarat A, Sarhan O, Hassouneh A, Abu Alhuda R, et al. Attitudes of Middle Eastern Societies towards Organ Donation: The Effect of Demographic Factors among Jordanian Adults. Res Health Sci. 2019 Dec 23;5(1):p1. DOI: https://doi.org/10.22158/rhs.v5n1p1

Gentry SE, Montgomery RA, Segev DL. Kidney Paired Donation: Fundamentals, Limitations, and Expansions. American Journal of Kidney Diseases. 2011 Jan;57(1):144–51. DOI: https://doi.org/10.1053/j.ajkd.2010.10.005

Malik S, Cole E. Foundations and Principles of the Canadian Living Donor Paired Exchange Program. Can J Kidney Health Dis. 2014 Jan 1;1:6. DOI: https://doi.org/10.1186/2054-3581-1-6

Li Y, Song PXK, Zhou Y, Leichtman AB, Rees MA, Kalbfleisch JD. Optimal Decisions for Organ Exchanges in a Kidney Paired Donation Program. Stat Biosci. 2014 May 13;6(1):85–104. DOI: https://doi.org/10.1007/s12561-013-9082-0

Penn medicine. Kidney paired donation increases living kidney transplantation . (n.d.). https://www.pennmedicine.org/for-health-care-professionals/for-physicians/physician-education-and-resources/clinical-briefings/2019/november/living-donor-paired-kidney-exchange-for-kidney-transplantation.

WHO Guiding Principles on Human Cell, Tissue and Organ Transplantation. Cell Tissue Bank. 2010 Nov 4;11(4):413–9. DOI: https://doi.org/10.1007/s10561-010-9226-0